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With many research and study, combined therapy with retinoids, Benzoyl peroxide gels and topical antibiotics are found to be most effective in treating most of the acne infections.

With this type of therapy, the retinoids prevents or removes comedones, whereas benzoyl peroxide or any other topical antibiotics eradicates P.Acnes. The retinoids also enhances absorption of the other medications. Sometimes irritation reactions limit the use of this combination therapy. So before you apply the combination therapy for your acne, there are few things you should know.

Always use retinoids creams or solution in the evening or bedtime as a single agent .

Apply benzoyl perixide gel or any other topical antibiotics prescribed in the morning.

If you acne have decreased then you must decrease the frequency of therapy and the concentration of the medications.

If you are using tretioin, apply the agent at different times, not simultaneously. Mixing highly saturated tretinoin with reactive oxidants like benzoyl perixide  might destroy both chemicals.

If you have any questions regarding use of combination therapy ask us at DermaTalk Skin Care Forum


  1. L. Rutger
    January 15, 2009 at 10:09 pm

    I too have acne. I was searching the internet and found http://www.skinterra.com and did a skincare analysis. The recommendations by one of their skin care consultants was great. I purchased the products and even saved 15% as a new customer.

  2. Azazael
    February 27, 2009 at 4:01 pm

    Hmm, very cognitive post.
    Is this theme good unough for the Digg?

  3. Brady Bryant
    June 13, 2010 at 11:06 am

    Retinoids are great for reducing visible wrinkle marks on the face.”..

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