Benzoyl peroxide (BPO) is a commonly used topical treatment for mild acne which was introduced in 1934. It is safe preparation for all adults and children, and it can be used in pregnancy too. Despite the fact that there are only few randomized trials that have been published, BPO is considered the standard topical treatment in mild acne.
Benzoyl peroxide has a potent bacteriostatic effect with a reduction of p.Acne within 2 days and a reduction in lesion count after 4 days of application. Benzoyl peroxide will also reduce the size and number of comedones present and may inhibit sebum secretion.
Benzoyl peroxide prescription and many other over-the-counter preparation can be obtained in various strength from 2.5% to 10%. It comes in alcohol-based gels or water based gels. The water-based preparation are less drying than the alcohol-based preparations. Benzoyl peroxide gels is normally applied once or twice daily.
The effect of Benzoyl peroxide is dose-dependent, The higher the dose the more it might be irritation. Normally 5 % BPO is enough to control mild acne. Skin irritation is the most common side effects so before you apply Benzoyl peroxide for the first time, it is adviced to skin-allergy test by applying small amount on antecubital area. As it has strong oxidative potential, So be aware that it might bleach colored and dark clothing or even hair.
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