Effect Of Global Warming On Skin Disorder

Global warming is a gradual increase in the average temperature of the earth’s near-surface air and oceans in recent decades and its projected continuation. It is the most current and widely discussed topics that might lead to ultimate end of existence of earth and and human being.

Global warming is directly or indirectly impacting on our lifes, including rise in sea levels, melting of ice,  and is responsible for significant changes in worldwide climate. Expert have agreed that melting of ice glaciers could release fungi, bacteria and virus incorporated during the freezing process that have been lying dormant for several thousands years that people might have thought have been eradicated already. Heat could make common virus develop strains to which people have no resistance and increase in the ranges of disease vector. This article will discuss the degree of impact and risk factors caused by global warming to our skin.

Ultraviolet Radiation:

Although Sun is the main factor for the existence of life on earth, but scientist believe that continue depletion of ozone layer has significient negative inpact on our skin too. Ultra violet rays are subdivided into three categories depending on their wave lengths, UVA-400-320 nm; UVB-320-290 nm; UVC-290-200 nm. Among all UVB radiation is by far the most harmful radiation that directly affect the skin causing different pigmentation disorder and increase risk of skin cancer. As ozone layer control the radiation, but recent depletion of ozone layer has increased the chances of many skin disease. Scientists believe that increase of temperature by 2% for a long-term due to changes of climate, might increase the carcinogenic effect of ultraviolet radiation by 10%.

Effects of Solar UVR on the Normal Skin The effects of UVR on skin can be classified into 2 caterogies depending on the duration of exposure .

Acute exposure:

Acute over exposure to Solar UVR might cause sunburn also called erythema. The redness of skin in sunburn is due to increase blood content of the skin due to the dilation of the superficial blood vessels in the skin. Excessive exposure might also results in blistering, swelling and peeling. It is estimated that UVA radiation contributes about 15-20% of sunburn reactions though it is less harmful than UVB. Another effects of exposure to UVR is tanning which is darkening of exposed skin due to UVA and invisible radiation. Immediate tanning can be noticed within 5-10 minutes and normally fades within 1-2 hours. Delayed tanning can be noticed after 1-2 days of sun exposure and persist for weeks to months.

Chronic Exposure

Chronic exposure to UVR might result in aging of skin normally called photoaging. Dryness, deep wrinkle, skin furrows, loss of elasticity, sagging, pigmentation and telangiectasia are the most common symptoms observed. Another common risk factors of Chronic exposure to UVR is Non-Melanoma Skin Cancer ( NMSC) . Most common form of NMSC are Squamous cell carcinoma ( SCC) and basal cell carcinoma ( BCC). BCC accounts for about 80% of all NMSC. Its is estimated that each 1% loss of total ozone layer have 3%-5% increase risk of skin cancer. It is believed that the increase in incidence of Melanoma is due to the changing pattern of sun exposure.

Impact of global warming in Sebaceous Glands and Acne:

The ideal temperature of  a human body is around 98.2°F.  Sweat glands and Sebaceous glands are heat sensitive and rapidly produce their secretions. As the temperature rises the activity of sebaseous glands increases resulting is over production of sebum, as a result sebum with dead cells together clogs the hair follicles and finally acne breakouts occur. Other oraganism like Staphylococcus and Streptococcus can colonize human in warmer climate resulting in many skin diseases which they cause.

Finally, We all should understand that global warming is a real serious issue which is affectiving us and our life directly on indirectly whether its environmental or medical. The solution is within us to stop this devastation by educating ourself and others with self awareness and health education.

Increased Incidence Of Skin Cancer Among Asian Living In Singapore

A Journal published at “Journal of the American Academy of dermatology” concludes that Incidence of skin cancer among peoples of singapore has increased from 1968 to 2006 and especially among older chinese.

The incidence rates of skin cancers in Caucasian populations are increasing. There is little information on skin cancer trends in Asians, who have distinctly different skin types. So this articles focus to study skin cancer incidence rates and time trends among the 3 Asian ethnic groups in Singapore.

These data of skin cancer were analyzed from the Singapore Cancer Registry from 1968 to 2006 using the Poisson regression model.

The data reports that there were 4044 reported cases of basal cell carcinoma, 2064 of squamous cell carcinoma, and 415 of melanoma. Overall skin cancer incidence rates increased from 2.9/100,000 in 1968 to 1972 to 8.4/100,000 in 1998 to 2002, declining to 7.4/100,000 in 2003 to 2006. Among older persons (?60 years), basal cell carcinoma rates increased the most, by 18.9/100,000 in Chinese, 6.0/100,000 in Malays, and 4.1/100,000 in Indians from 1968 to 1972 to 2003 to 2006. Squamous cell carcinoma rates among those aged 60 years and older increased by 2.3/100,000 in Chinese and by 1/100,000 in Malays and Indians. Melanoma rates were constant for all 3 races. Skin cancer rates among the fairer-skinned Chinese were approximately 3 times higher than in Malays and Indians, who generally have darker complexions.

Although appropriate population denominators were used, lack of data from 2007 could have affected the results for the last time period, which comprised 4 instead of 5 years.

Adapted from the article provided by Journal of the American Academy of dermatology

Any Doubtful Non Itchy Painless Mass Could Be Skin Cancer

When cells of the skin multiply in a haphazard manner,they form small masses on the skin, and these are known as skin cancer.

There are mainly three types of skin cancer. The most common are squamous cell carcinoma and basal cell carcinoma. Squamous cell carcinoma present ulcerated masses on the lower half of the face, while basal cell carcinoma are skin coloured, pearly white or coloured masses on the upper half of the face. Both can be cured by surgical method.

Melanoma, on the other hand, is the most lethal cancers. They are like coloured moles, which grow repidly,can bleed,are itchy or change colour. They have to be excised very early. Any doubtful lesion or mass on the skin which doesn’t itch, painless has to be checked to rule out skin cancer.

Skin cancer is diagnosed clinically and confirmed by histopathological examination. If you have doubt or if you suspect of skin cancer it is better to consult a dermatologist as soon as possible for quick management and treatment.

New Drug For Skin Cancer Approaching Commercialization

A drug that is activated by light can be a quick, simple, and cheap treatment for tens of thousands of patients with skin cancer in Sweden alone. Researcher Leif Eriksson’s team at Örebro University in Sweden has now received about SEK 4 million from government research financiers, the Swedish Research Council and Vinnova, to further develop and commercialize the method.

The new drug that the Örebro researchers have developed is based on the use of photo-dynamic therapy in cancer treatment. In short, this is a drug that after reorganization in the cell is activated by light, which in turn leads to chemical reactions that effectively kills cancer cells.

With this method, a majority of the some 30,000 new cases of skin cancer discovered each year in Sweden alone could be treated quickly, simply, and cost effectively. This is also true for pre-stages of skin cancer, so-called actinic keratosis.

“It’s extremely gratifying that two of the most important research financiers in Sweden so actively support our research,” says Leif Eriksson, professor of biophysical and theoretical chemistry at Örebro University.

Leif Eriksson’s drug research has grown out of the Örebro Life Science Center (OLSC), an interdisciplinary, internationally acclaimed research node at Örebro University. Research on new forms of treatment for skin tumors is also being conducted in collaboration with Associate Professor Lennart Löfgren at the Center for Head and Neck Oncology at Örebro University Hospital.

“Our drug, and the new treatment concept we are developing together with researchers in Belfast, has tremendous potential. In the coming year we will also see further patents as a direct result of the collaboration with other research teams within the OLSC, including treatments for atherosclerosis and autoimmune disorders such as rheumatism,” says Leif Eriksson.

The development of new drugs is being carried out with the aid of advanced computer modeling – a method that has proven to be highly successful.

“We provide the expertise in the theoretical description of new drugs. In our research we aim to describe at a detailed level what they should look like, what properties they should have to match the right targets in the body, what happens if we alter the molecules in different ways, etc. We then put this together through collaboration with experimental or clinically active research teams within OLSC and at the hospital, which makes the research exciting and dynamic,” says Leif Eriksson

Adapted from materials provided by Vetenskapsrådet (The Swedish Research Council), via AlphaGalileo